
Dogs most at risk are young, generally large breeds(german shepards and dobermans especially) that spend a lot of time outdoors. Dogs over 3 or 4 years old aren't as likely to get RMSF, possibly having acquired an immunity.
The onset of the disease is rapid. Four or five days after being bitten, the dog will become feverish (up to 105 degrees). Symptoms may include depression, loss of appetite, swollen lymph nodes, bruising on the skin or gums, tiny hemorrhages under the skin, muscle pain, retinal hemorrage, swollen or painful joints. A staggering gait, difficulty keeping his balance, is the dog's most common neurological sign. Seizures are possible. A decrease in the platelets responsible for clotting (thrombocytopenia), is the most consistent finding in blood tests.
If left untreated, RMSF either kills quickly (the disease runs its course in approximately two weeks) or the dog gets over it and is then immune. Symptoms may range from slight through severe to fatal.
It takes two to three weeks for antibodies to be detectable but then their numbers rise sharply for several weeks before they level off and begin a long, slow, gradual decline over many months. Obviously the timeline is very tight here, so, since research indicates that death from untreated RMSF is more common than previously thought, a dog that appears to have it should be treated immediately without waiting for test results to come back.
It's in this stage that the outlook for a cure is best. Very early on, however, testing is probably useless; until ten days to two weeks after infection, the immune system will not have had time to make sufficient antibodies for the tests to detect.
The acute stage over, the disease passes into the subclinical stage. This simply means a stage in which no symptoms are present. Cure, or at the very least, containment of the disease so that it cannot progress, is still a good possibility in this stage, which may last for years.
If the disease progresses to chronic, the outlook is grave, particularly in E. risticii and E. canis. Symptoms show up with a vengeance at this point. There are a lot of symptoms and they are easily mistaken for other diseases: intermittent fever or loss of appetite lethargy, total loss of appetite, gradual loss of body condition (esp. along the spine and around the eyes), viral tumors on the face/mouth/muzzle, hemorrhaging even when the blood count looks normal, clotting problems, low or high calcium levels, seizures, muscle wasting, skin infections, neurological signs, diarrhea, low platelet count, urine too alkaline, vomiting, hyper-reflective eyes, low white blood cell count, bleeding from nose or eyes, signs of arthritis, pneumonia, cough, kidney failure, increased thirst and urination, incoordination, neck or back pain, bleeding under the skin or a rash, swelling of the legs or joints, enlarged lymph nodes, irreversible bone marrow suppression.
The brown dog tick, is the usual culprit in the transmission of babesiosis; however, transmission has also occurred by direct, blood to blood transfer in fighting dogs, and by the transfusion of infected blood. Infected bitches have been known to pass the disease to pups in the womb.
In the United States, Babesiosis canis shows up mostly in the South but it does occur in other areas.. Babesiosis gibsoni is found all over the country but most often appears in pit bull terriers.
The dogs most at risk are those brought into an endemic area. These dogs are prone to severe infection. Evidently, those that are born in an area where babesiosis is prevalent get the infection while they're still protected by the colostrum in the mother's milk and, as a result, become immune carriers.
Clinical signs include fever that comes and goes, red or orange-colored urine, loss of appetite and the dog becomes too thin, his bones are more prominent, his coat is dull and there is at least some loss of muscle mass.
Because there is a foreign invader in the red blood cells, the dog's immune system will start to destroy them, adding to the destruction the babesia are causing. A drop in the platelets which aid in blood clotting can make things even worse; this is especially a problem in B. gibsoni. As if that weren't enough, the immune system may begin destroying uninfected RBCs as well. Half of all dogs with babesiosis will need transfusion. Severe inflammation is common and localized inflammation of the central nervous system can occur.
Use a tool specifically made for removing ticks, a pair of sharp tweezers (not blunt ones) or a small pair of curved forceps.
Grab the tick right behind the head, i.e., as close to the skin as you can get, and PULL SLOWLY - STRAIGHT OUT. Don't twist the tick, it isn't made to unscrew. The tick's hypostome, the part that penetrates the dog, has barbs like fishhooks, so slow, easy and straight out is the way you want to go. Do not pull out ticks with your bare hands, you are putting yourself in risk to contract the disease!
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